SCHEMBL8430252

SCHEMBL8430252

FCCCC1CCC(c2ccc(OC(F)(F)F)c(F)c2)CC1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 6/20 0.36
SLC7A5 Q01650 1/20 0.36
PDE2A O00408 8/20 0.34
ESR2 Q92731 1/20 0.33
CHRM2 P08172 1/20 0.33
CTSK P43235 1/20 0.33
NAAA Q02083 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8767778 0.90 EPHX2 (0.36) EPHX2SLC7A5PDE2AESR2CHRM2
SCHEMBL8767773 0.90 EPHX2 (0.36) EPHX2SLC7A5PDE2AESR2CHRM2
SCHEMBL8767044 0.88 EPHX2 (0.35) EPHX2PDE2AESR2CHRM2
SCHEMBL8767039 0.88 EPHX2 (0.35) EPHX2PDE2AESR2CHRM2
SCHEMBL8453777 0.87 EPHX2 (0.31) EPHX2SLC7A5PDE2A
SCHEMBL8453779 0.87 EPHX2 (0.31) EPHX2SLC7A5PDE2A
SCHEMBL8767623 0.86 PDE2A (0.38) EPHX2PDE2AESR2CHRM2
SCHEMBL8767621 0.86 PDE2A (0.38) EPHX2PDE2AESR2CHRM2
SCHEMBL12997536 0.86 EPHX2 (0.45) EPHX2PDE2ACTSKNAAA
SCHEMBL8430317 0.85 P2RX7 (0.34) EPHX2PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718264-B1 A liquid crystalline compound containing fluorine atom substituted alkyl group(s) and a liquid crystal composition CHISSO CORP (JP) 1999-11-17 EP disclosed
US-5702641-A ELECTRICAL AND CHEMICAL STABILITY CHISSO CORPORATION (JP) 1997-12-30 US disclosed
EP-0718264-A1 A liquid crystalline compound containing fluorine atom substituted alkyl group(s) and a liquid crystal composition Chisso Corporation (JP) 1996-06-26 EP disclosed