Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20599481 | 0.81 | TP53 (0.40) | TP53 | |
| SCHEMBL21998212 | 0.78 | TP53 (0.50) | TP53TSHR | |
| SCHEMBL21996348 | 0.78 | TP53 (0.50) | TP53TSHR | |
| SCHEMBL28738588 | 0.78 | TP53 (0.50) | TP53TSHR | |
| SCHEMBL8583856 | 0.76 | TP53 (0.47) | TP53TSHR | |
| SCHEMBL5675218 | 0.76 | TP53 (0.47) | TP53TSHR | |
| SCHEMBL8583868 | 0.76 | TP53 (0.47) | TP53TSHR | |
| SCHEMBL2932270 | 0.72 | — | — | |
| SCHEMBL2687210 | 0.72 | — | — | |
| SCHEMBL55048 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004787-A | ISOLATING MACROLIDE POLYKETIDE BIOSYNTHETIC GENE, IDENTIFYING ENZYMATIC ACTIVITIES, MUTATING NUCLEOTIDE SEQUENCE, TRANSFORMING INTO A POLYKETIDE PRODUCING MICROORGANISM, CULTURING, AND ISOLATING PRODUCT | ABBOTT LABORATORIES (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0626806-A1 | METHOD OF DIRECTING BIOSYNTHESIS OF SPECIFIC POLYKETIDES | ABBOTT LABORATORIES (US) | 1994-12-07 | — | — | EP | disclosed |
| WO-1993013663-A1 | METHOD OF DIRECTING BIOSYNTHESIS OF SPECIFIC POLYKETIDES | ABBOTT LABORATORIES (US) | 1993-07-22 | — | — | WO | disclosed |