SCHEMBL20599481

SCHEMBL20599481

CC(C(=O)O)C(F)C(F)F

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.40
SLC7A5 Q01650 1/20 0.33
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6667744 0.81
SCHEMBL1031474 0.81
SCHEMBL1032112 0.81
SCHEMBL8430261 0.81 TP53 (0.41) TP53
SCHEMBL11358364 0.74 TP53 (0.38) TP53SLC7A5
SCHEMBL27331253 0.74 LMNA (0.30)
SCHEMBL457721 0.74 SLC7A5 (0.50) TP53SLC7A5MAPT
SCHEMBL1261744 0.74 TP53 (0.50) TP53SLC7A5
SCHEMBL18211012 0.74 TP53 (0.50) TP53SLC7A5
SCHEMBL812149 0.73 TP53 (0.57) TP53SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117441254-A Electrolyte for secondary battery, and electronic device 宁德新能源科技有限公司 2024-01-23 CN claimed
CN-116706232-A Electrolyte of secondary battery, secondary battery and electronic device 宁德新能源科技有限公司 2023-09-05 CN claimed
CN-117832586-A Electrochemical device and electronic device 东莞新能源科技有限公司 2024-04-05 CN disclosed
US-20240066131-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2024-02-29 US disclosed
CN-117441254-A Electrolyte for secondary battery, and electronic device 宁德新能源科技有限公司 2024-01-23 CN disclosed
US-20240016895-A1 HEPCIDIN MIMETICS FOR TREATMENT OF SICKLE CELL DISEASE PROTAGONIST THERAPEUTICS, INC. 2024-01-18 US disclosed
US-20240018189-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2024-01-18 US disclosed
US-11753443-B2 Conjugated hepcidin mimetics PROTAGONIST THERAPEUTICS, INC. (US) 2023-09-12 US disclosed
CN-112739753-B Resin film and method for producing same 东丽株式会社 2023-09-12 CN disclosed
CN-116706232-A Electrolyte of secondary battery, secondary battery and electronic device 宁德新能源科技有限公司 2023-09-05 CN disclosed
CN-116053591-B Electrolyte of secondary battery, secondary battery and electronic device 宁德新能源科技有限公司 2023-06-27 CN disclosed
CN-116053591-A Electrolyte of secondary battery, secondary battery and electronic device 宁德新能源科技有限公司 2023-05-02 CN disclosed
US-20200361992-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. 2020-11-19 US disclosed
WO-2019000237-A1 3-(1H-PYRAZOL-4-YL)PYRIDINE ALLOSTERIC MODULATORS OF M4 MUSCARINIC ACETYLCHOLINE RECEPTOR MERCK SHARP & DOHME CORP. (US) 2019-01-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018189-A1 CONJUGATED HEPCIDIN MIMETICS HAMP, VIP, HDGF TP53 2998/4885SLC7A5 927/4885MAPT 4733/4885
US-20200361992-A1 CONJUGATED HEPCIDIN MIMETICS HAMP, VIP, HDGF TP53 2998/4885SLC7A5 927/4885MAPT 4733/4885
US-11753443-B2 Conjugated hepcidin mimetics HAMP, VIP, HDGF TP53 2998/4885SLC7A5 927/4885MAPT 4733/4885
US-20240016895-A1 HEPCIDIN MIMETICS FOR TREATMENT OF SICKLE CELL DISEASE HAMP, HBG1, HBG2 TP53 1738/4885SLC7A5 648/4885MAPT 4844/4885
US-20240066131-A1 CONJUGATED HEPCIDIN MIMETICS HAMP, VIP, HDGF TP53 2998/4885SLC7A5 927/4885MAPT 4733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.