Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432156 | 0.88 | CNR1 (0.53) | CNR1CNR2FFAR1TSHRPPARG | |
| SCHEMBL8432044 | 0.86 | CNR1 (0.54) | CNR1CNR2FFAR1TSHRDHFR | |
| SCHEMBL8428449 | 0.86 | CNR1 (0.54) | CNR1CNR2FFAR1TSHRDHFR | |
| SCHEMBL8429999 | 0.86 | CNR1 (0.51) | CNR1CNR2FFAR1TSHRDHFR | |
| SCHEMBL8428045 | 0.83 | CNR2 (0.57) | CNR1CNR2FFAR1TSHRDHFR | |
| SCHEMBL10767355 | 0.83 | POLB (0.56) | CNR1CNR2TSHRLTB4RMEN1 | |
| SCHEMBL8714213 | 0.83 | POLB (0.56) | CNR1CNR2TSHRLTB4RMEN1 | |
| SCHEMBL4419943 | 0.81 | POLB (0.57) | CNR1CNR2TSHRLTB4RMEN1 | |
| SCHEMBL2046234 | 0.79 | PPARA (0.52) | CNR1CNR2FFAR1DHFRPPARG | |
| SCHEMBL27788117 | 0.79 | POLB (0.60) | CNR1CNR2FFAR1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880147-A | Amide derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prohylactic use | SANKYO COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |