Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | F13A1 | P00488 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | APLNR | P35414 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10767355 | 1.00 | POLB (0.56) | POLBCNR1TSHRLTB4RHSD17B10 | |
| SCHEMBL4419943 | 0.98 | POLB (0.57) | POLBCNR1TSHRLTB4RHSD17B10 | |
| SCHEMBL27788117 | 0.95 | POLB (0.60) | POLBCNR1TSHRHSD17B10CNR2 | |
| SCHEMBL8708565 | 0.88 | MTNR1A (0.58) | CNR1TSHRCNR2APLNRMEN1 | |
| SCHEMBL490637 | 0.88 | POLB (0.71) | POLBHSD17B10APLNRALDH1A1 | |
| SCHEMBL8432044 | 0.87 | CNR1 (0.54) | CNR1TSHRLTB4RCNR2MEN1 | |
| SCHEMBL8428449 | 0.87 | CNR1 (0.54) | CNR1TSHRLTB4RCNR2MEN1 | |
| SCHEMBL27621740 | 0.87 | HSD17B10 (0.65) | POLBLTB4RHSD17B10 | |
| SCHEMBL11433418 | 0.85 | HSD17B10 (0.67) | POLBHSD17B10 | |
| SCHEMBL8428045 | 0.84 | CNR2 (0.57) | CNR1TSHRLTB4RCNR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-H10316641-A | CARBOXYLIC ACID DERIVATIVE | SANKYO CO LTD | 1998-12-02 | — | — | JP | disclosed |
| JP-10316641-A | — | — | 0001-01-01 | — | — | JP | disclosed |