Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 4/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 2/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431707 | 1.00 | PPARA (0.49) | PPARACTSSCTSKMEN1ALDH1A1 | |
| SCHEMBL8430410 | 1.00 | PPARA (0.49) | PPARACTSSCTSKMEN1ALDH1A1 | |
| SCHEMBL8430408 | 1.00 | PPARA (0.49) | PPARACTSSCTSKMEN1ALDH1A1 | |
| SCHEMBL8640881 | 1.00 | PPARA (0.49) | PPARACTSSCTSKMEN1ALDH1A1 | |
| SCHEMBL8431546 | 0.94 | PPARA (0.55) | PPARACTSSCTSKMEN1ALDH1A1 | |
| SCHEMBL8430542 | 0.94 | PPARA (0.55) | PPARACTSSCTSKMEN1ALDH1A1 | |
| SCHEMBL8432480 | 0.92 | CTSS (0.48) | PPARACTSSCTSKMEN1ALDH1A1 | |
| SCHEMBL8432912 | 0.91 | PPARA (0.48) | PPARACTSSCTSKMEN1ALDH1A1 | |
| SCHEMBL8434087 | 0.90 | PPARA (0.60) | PPARACTSSCTSKMEN1ALDH1A1 | |
| SCHEMBL8432283 | 0.90 | PPARA (0.60) | PPARACTSSCTSKMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919769-A | ANTIINFLAMMATORY AGENT | KANEBO, LTD (JP) | 1999-07-06 | — | — | US | disclosed |
| EP-0859005-A1 | FUCOSE DERIVATIVES, DRUGS CONTAINING THE SAME AS ACTIVE INGREDIENT, AND INTERMEDIATES FOR PRODUCING THE SAME | KANEBO, LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |