SCHEMBL8430730

SCHEMBL8430730

C=C(C)C(=O)OC(OC(=O)CC(C)=O)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
TSHR P16473 1/20 0.35
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL372920 0.85 ALDH1A1 (0.44) ALDH1A1TSHRTHRB
SCHEMBL22462696 0.78 ALDH1A1 (0.43) ALDH1A1MGAMGAASIMGAM2
SCHEMBL29686696 0.78 MGAM (0.36) ALDH1A1MGAMGAASIMGAM2
SCHEMBL112876 0.77 TSHR (0.42) ALDH1A1MGAMGAASIMGAM2
SCHEMBL1024183 0.75 TSHR (0.41) ALDH1A1MGAMGAASIMGAM2
SCHEMBL27536885 0.75 TSHR (0.41) ALDH1A1MGAMGAASIMGAM2
SCHEMBL28487160 0.75 TSHR (0.41) ALDH1A1MGAMGAASIMGAM2
SCHEMBL2670312 0.74 ALDH1A1 (0.34) ALDH1A1TSHR
SCHEMBL273177 0.74 MGAM (0.39) ALDH1A1MGAMGAASIMGAM2
Methacrylic Acid SCHEMBL25423391 0.72 TSHR (0.39) ALDH1A1MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0643326-B1 New type of polymer latex and its use as plasticizer in a photographic material AGFA GEVAERT NV (BE) 1999-12-01 EP disclosed
US-5478710-A Obtained by radical emulsion polymerization; glass transition temperature AGFA-GEVAERT, N.V. (BE) 1995-12-26 US disclosed
EP-0643326-A1 New type of polymer latex and its use as plasticizer in a photographic material AGFA-GEVAERT N.V. (BE) 1995-03-15 EP disclosed
US-5310639-A Photographic element containing stress absorbing intermediate layer EASTMAN KODAK COMPANY (US) 1994-05-10 US disclosed
US-5300417-A Blend of polymer and hydrophilic colloid EASTMAN KODAK COMPANY (US) 1994-04-05 US disclosed
US-5298376-A Photographic silver halide material with improved color saturation EASTMAN KODAK COMPANY (US) 1994-03-29 US disclosed
EP-0535535-A1 Photographic silver halide material with improved color saturation EASTMAN KODAK COMPANY (US) 1993-04-07 EP disclosed
EP-0520393-A1 Photographic element containing stress absorbing protective layer EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-12-30 EP disclosed
EP-0520394-A2 Photographic element containing stress absorbing intermediate layer EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-12-30 EP disclosed
EP-0358187-A2 Tabular grain photographic elements exhibiting reduced pressure sensitivity (II) EASTMAN KODAK COMPANY (US) 1990-03-14 EP disclosed