Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.56 |
| ▸ | GAA | P10253 | 11/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.56 |
| ▸ | MEN1 | O00255 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5084625 | 0.85 | MAPT (0.67) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL5080900 | 0.83 | MAPT (0.64) | MAPTGAAKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9797327 | 0.81 | MAPT (0.61) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL5605306 | 0.79 | MAPT (0.59) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL5604998 | 0.79 | MAPT (0.59) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL1336716 | 0.78 | MAPT (0.62) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL11742148 | 0.78 | MAPT (0.59) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL5604588 | 0.78 | MAPT (0.58) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL8537743 | 0.78 | MAPT (0.58) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL5605277 | 0.78 | MAPT (0.58) | MAPTGAAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859007-A | TREATMENT OF DIABETES, OBESITY | GLAXO WELLCOME INC. (US) | 1999-01-12 | — | — | US | disclosed |