SCHEMBL5080900

SCHEMBL5080900

Nc1cc(N)c(Nc2ccccc2)cc1Nc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 14/20 0.64
▸ ALDH1A1 P00352 12/20 0.64
▸ GAA P10253 11/20 0.64
▸ KDM4E B2RXH2 10/20 0.64
▸ MEN1 O00255 8/20 0.64
▸ KMT2A Q03164 8/20 0.64
▸ LMNA P02545 4/20 0.64
▸ CYP1A2 P05177 2/20 0.64
▸ CYP2C9 P11712 2/20 0.64
▸ CYP2C19 P33261 2/20 0.64
▸ CYP2D6 P10635 1/20 0.64
▸ HPGD P15428 5/20 0.63
▸ SMN1; SMN2 Q16637 4/20 0.63
▸ HTT P42858 3/20 0.63
▸ HSD17B10 Q99714 5/20 0.56
▸ L3MBTL1 Q9Y468 4/20 0.56
▸ GFER P55789 3/20 0.56
▸ THRB P10828 1/20 0.56
▸ TDP1 Q9NUW8 7/20 0.53
▸ ALOX15 P16050 4/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9797327 0.98 MAPT (0.61) MAPTALDH1A1GAAKDM4EMEN1
SCHEMBL5084625 0.93 MAPT (0.67) MAPTALDH1A1GAAKDM4EMEN1
SCHEMBL22102775 0.92 MAPT (0.65) MAPTALDH1A1GAAKDM4EMEN1
SCHEMBL5604998 0.86 MAPT (0.59) MAPTALDH1A1GAAKDM4EMEN1
SCHEMBL5605306 0.86 MAPT (0.59) MAPTALDH1A1GAAKDM4EMEN1
SCHEMBL10816038 0.86 MAPT (0.54) MAPTALDH1A1GAAKDM4EMEN1
SCHEMBL5605277 0.85 MAPT (0.58) MAPTALDH1A1GAAKDM4EMEN1
SCHEMBL5604588 0.85 MAPT (0.58) MAPTALDH1A1GAAKDM4EMEN1
SCHEMBL8537743 0.85 MAPT (0.58) MAPTALDH1A1GAAKDM4EMEN1
SCHEMBL8430768 0.83 MAPT (0.56) MAPTALDH1A1GAAKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4578434-A POLYBENZIMIDAZOLES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1986-03-25 — — US claimed
US-20220016009-A1 SYMMETRIC AZOMETHINE DIRECT DYES, PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF L'OREAL (FR) 2022-01-20 — — US disclosed
US-11174258-B2 Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2021-11-16 — — US disclosed
EP-3554467-B1 SYMMETRIC AZOMETHINE DIRECT DYES, PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF OREAL (FR) 2020-11-25 — — EP disclosed
WO-2018109156-A1 SYMMETRIC AZOMETHINE DIRECT DYES, PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF L'OREAL (FR) 2018-06-21 — — WO disclosed
WO-2017093958-A1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2017-06-08 — — WO disclosed
EP-1462471-B1 Dielectric films and materials therefor DAICEL CHEM (JP) 2008-07-30 — — EP disclosed
EP-1462470-B1 Dielectric films and materials therefor DAICEL CHEM (JP) 2007-08-29 — — EP disclosed
US-20070078256-A1 Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-04-05 — — US disclosed
US-7186454-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-06 — — US disclosed
US-7090925-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-15 — — US disclosed
EP-1683822-A1 PREPOLYMER, PREPOLYMER COMPOSITION, HIGH MOLECULAR WEIGHT POLYMER HAVING STRUCTURE CONTAINING HOLE AND ELECTRICALLY INSULATING FILM Daicel Chemical Industries, Ltd. (JP) 2006-07-26 — — EP disclosed
EP-1681284-A1 AROMATIC POLYAMINE DERIVATIVE Daicel Chemical Industries, Ltd. (JP) 2006-07-19 — — EP disclosed
US-20040192880-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-30 — — US disclosed
EP-1462470-A1 Dielectric films and materials therefor Daicel Chemical Industries, Ltd. (JP) 2004-09-29 — — EP disclosed
EP-1462471-A1 Dielectric films and materials thereof Daicel Chemical Industries, Ltd. (JP) 2004-09-29 — — EP disclosed
US-20040175858-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-09 — — US disclosed
US-5773197-A Integrated circuit device and process for its manufacture INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1998-06-30 — — US disclosed
US-3951920-A Permselective polymeric membrane prepared from polybenzimidazoles TEIJIN LIMITED (JA) 1976-04-20 — — US disclosed
US-3951934-A Polymerization of acrylamide in the presence of water-soluble nitrogen compounds NITTO CHEMICAL INDUSTRY CO., LTD. (JA) 1976-04-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220016009-A1 SYMMETRIC AZOMETHINE DIRECT DYES, PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF KRT18, IK, H1-5 MAPT 594/4885ALDH1A1 582/4885GAA 4811/4885
US-11174258-B2 Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes KCNH2, KCNH3, KCNJ2 MAPT 2580/4885ALDH1A1 397/4885GAA 1647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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