Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.68 |
| ▸ | CSNK1D | P48730 | 13/20 | 0.64 |
| ▸ | ACP1 | P24666 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | SCN4A | P35499 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5683714 | 0.84 | DYRK1A (0.68) | DYRK1ACSNK1DACP1EPHX2SCN4A | |
| SCHEMBL2116732 | 0.84 | KDM4E (0.64) | DYRK1ACSNK1DACP1EPHX2SCN4A | |
| SCHEMBL3791611 | 0.82 | DYRK1A (0.78) | DYRK1ACSNK1DACP1CYP2D6LRRK2 | |
| SCHEMBL28878445 | 0.81 | DYRK1A (0.64) | DYRK1ACSNK1DACP1EPHX2SCN4A | |
| SCHEMBL29974674 | 0.81 | DYRK1A (0.64) | DYRK1ACSNK1DACP1EPHX2SCN4A | |
| SCHEMBL6191383 | 0.81 | DYRK1A (0.76) | DYRK1ACSNK1DACP1CYP2D6LRRK2 | |
| SCHEMBL25867794 | 0.80 | DYRK1A (0.63) | DYRK1ACSNK1DACP1EPHX2SCN4A | |
| SCHEMBL212708 | 0.80 | DYRK1A (0.63) | DYRK1ACSNK1DACP1EPHX2SCN4A | |
| SCHEMBL30116088 | 0.79 | NPC1 (0.68) | DYRK1ACSNK1DACP1EPHX2SCN4A | |
| SCHEMBL3026789 | 0.79 | DYRK1A (0.68) | DYRK1ACSNK1DACP1EPHX2SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788491-B1 | 6-POLYFLUOROALKOXY AND 6-POLYFLUOROALKYL-2-AMINOBENZOTHIAZOLE DERIVATIVES | RHONE POULENC RORER SA (FR) | 1999-12-01 | — | — | EP | claimed |
| US-5795903-A | 6-polyfluoroalkoxy-and 6-polyfluoroalkyl-2-aminobenzothiazole derivatives | RHONE-POULENC RORER S.A. (FR) | 1998-08-18 | — | — | US | claimed |
| EP-0788491-A1 | 6-POLYFLUOROALKOXY AND 6-POLYFLUOROALKYL-2-AMINOBENZOTHIAZOLE DERIVATIVES | Aventis Pharma S.A. (FR) | 1997-08-13 | — | — | EP | claimed |
| WO-1996013492-A1 | 6-POLYFLUOROALKOXY AND 6-POLYFLUOROALKYL-2-AMINOBENZOTHIAZOLE DERIVATIVES | RHONE-POULENC RORER S.A. (FR) | 1996-05-09 | — | — | WO | claimed |
| EP-0788491-B1 | 6-POLYFLUOROALKOXY AND 6-POLYFLUOROALKYL-2-AMINOBENZOTHIAZOLE DERIVATIVES | RHONE POULENC RORER SA (FR) | 1999-12-01 | — | — | EP | disclosed |
| US-5795903-A | 6-polyfluoroalkoxy-and 6-polyfluoroalkyl-2-aminobenzothiazole derivatives | RHONE-POULENC RORER S.A. (FR) | 1998-08-18 | — | — | US | disclosed |
| EP-0788491-A1 | 6-POLYFLUOROALKOXY AND 6-POLYFLUOROALKYL-2-AMINOBENZOTHIAZOLE DERIVATIVES | Aventis Pharma S.A. (FR) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996013492-A1 | 6-POLYFLUOROALKOXY AND 6-POLYFLUOROALKYL-2-AMINOBENZOTHIAZOLE DERIVATIVES | RHONE-POULENC RORER S.A. (FR) | 1996-05-09 | — | — | WO | disclosed |