⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842819 | 0.86 | — | — | |
| SCHEMBL1745100 | 0.79 | — | — | |
| SCHEMBL4048543 | 0.77 | — | — | |
| SCHEMBL1454524 | 0.77 | — | — | |
| SCHEMBL13922054 | 0.77 | — | — | |
| SCHEMBL4641210 | 0.76 | — | — | |
| SCHEMBL7859107 | 0.75 | — | — | |
| SCHEMBL4047497 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL10918298 | 0.75 | — | — | |
| SCHEMBL5941933 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191542-A1 | Arylcyclobutylalkyl amines and their use as antidepressive medicines | The Boots Company PLC (GB) | 1986-08-20 | — | — | EP | claimed |
| US-9278969-B2 | Organic compounds | NOVARTIS AG (CH) | 2016-03-08 | — | — | US | disclosed |
| US-20140357621-A1 | Organic Compounds | NOVARTIS AG (CH) | 2014-12-04 | — | — | US | disclosed |
| EP-2256118-B1 | Condensed imidazolo derivatives for the inhibition of aromatase and the treatment of aldosterone related diseases | NOVARTIS AG (CH) | 2014-10-29 | — | — | EP | disclosed |
| US-8835646-B2 | Organic compounds | NOVARTIS AG (CH) | 2014-09-16 | — | — | US | disclosed |
| US-20130287789-A1 | Organic Compounds | NOVARTIS AG (CH) | 2013-10-31 | — | — | US | disclosed |
| US-20130196977-A1 | USE OF ORGANIC COMPOUNDS | FELDMAN DAVID LOUIS (US) | 2013-08-01 | — | — | US | disclosed |
| US-8436035-B2 | Organic compounds | NOVARTIS AG (CH) | 2013-05-07 | — | — | US | disclosed |
| EP-1919916-B1 | CONDENSED IMIDAZOLO DERIVATIVES FOR THE INHIBITION OF ALDOSTERONE SYNTHASE AND AROMATASE | NOVARTIS AG (CH) | 2013-04-03 | — | — | EP | disclosed |
| US-8314097-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-11-20 | — | — | US | disclosed |
| WO-2006041974-A1 | USE OF RENIN INHIBITORS FOR THE PREVENTION OR TREATMENT OF DIASTOLIC DYSFUNCTION OR DIASTOLIC HEART FAILURE | NOVARTIS AG (CH) | 2006-04-20 | — | — | WO | disclosed |
| CN-1365025-A | Positive imaging material | FUJI PHOTO FILM CO LTD (JP) | 2002-08-21 | — | — | CN | disclosed |
| US-5591562-A | SOLDER RESISTS, EPOXY RESINS WITH POLYMERIZABLE UNSATURATION AND QUATERNARY AMMONIUM, SULFONIUM OR PHOSPHONIUM GROUPS | SONY CORPORATION (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0719258-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| WO-1996002508-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-01 | — | — | WO | disclosed |
| WO-1995016662-A1 | ENANTIOMERIC RESOLUTION | ALBEMARLE CORPORATION (US) | 1995-06-22 | — | — | WO | disclosed |
| EP-0630354-A1 | MOLECULAR SIEVES CONTAINING AZO DYES. | BASF AG (DE) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993017965-A1 | MOLECULAR SIEVES CONTAINING AZO DYES | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-16 | — | — | WO | disclosed |
| EP-0380144-A1 | Process for producing optically active benzene-sulfonamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1990-08-01 | — | — | EP | disclosed |
| EP-0257787-A1 | Process for producing optically active benzene-sulfonamide derivates | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |