SCHEMBL8431409

SCHEMBL8431409

NCCCC[C@H](NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)NCC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PSMB1 P20618 1/20 0.39
▸ PSMB8 P28062 1/20 0.39
▸ PSMB9 P28065 1/20 0.39
▸ PSMB5 P28074 1/20 0.39
▸ PSMB10 P40306 1/20 0.39
▸ PSMB2 P49721 1/20 0.39
▸ SLC15A2 Q16348 1/20 0.38
▸ MMP2 P08253 1/20 0.37
▸ TUBB4A P04350 1/20 0.35
▸ TUBB P07437 1/20 0.35
▸ TUBA3C P0DPH7 1/20 0.35
▸ TUBA1B P68363 1/20 0.35
▸ TUBA4A P68366 1/20 0.35
▸ TUBB4B P68371 1/20 0.35
▸ TUBB3 Q13509 1/20 0.35
▸ TUBB2A Q13885 1/20 0.35
▸ TUBB8 Q3ZCM7 1/20 0.35
▸ TUBA3E Q6PEY2 1/20 0.35
▸ TUBA1A Q71U36 1/20 0.35
▸ TUBA1C Q9BQE3 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29484171 0.93 SLC15A2 (0.41) PSMB1PSMB8PSMB9PSMB5PSMB10
SCHEMBL9616877 0.92 MMP2 (0.39) PSMB1PSMB8PSMB9PSMB5PSMB10
SCHEMBL9200315 0.92 MMP2 (0.39) PSMB1PSMB8PSMB9PSMB5PSMB10
SCHEMBL8427968 0.92 MMP2 (0.39) PSMB1PSMB8PSMB9PSMB5PSMB10
SCHEMBL6116125 0.90 SLC15A2 (0.41) PSMB1PSMB8PSMB9PSMB5PSMB10
SCHEMBL6116135 0.90 SLC15A2 (0.41) PSMB1PSMB8PSMB9PSMB5PSMB10
SCHEMBL3357251 0.90 SLC15A2 (0.42) PSMB1PSMB8PSMB9PSMB5PSMB10
SCHEMBL3357272 0.90 SLC15A2 (0.42) PSMB1PSMB8PSMB9PSMB5PSMB10
Glycine SCHEMBL22289294 0.88 SLC15A2 (0.49) PSMB1PSMB8PSMB9PSMB5PSMB10
SCHEMBL29940001 0.88 SLC15A2 (0.49) PSMB1PSMB8PSMB9PSMB5PSMB10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116585283-B Lansoprazole enteric capsule and preparation method thereof 桂林华信制药有限公司 2024-11-22 — — CN claimed
CN-116585283-A Lansoprazole enteric capsule and preparation method thereof 桂林华信制药有限公司 2023-08-15 — — CN claimed
CN-116585283-B Lansoprazole enteric capsule and preparation method thereof 桂林华信制药有限公司 2024-11-22 — — CN disclosed
CN-116807990-B Esomeprazole magnesium enteric capsule and preparation method thereof 桂林华信制药有限公司 2024-09-24 — — CN disclosed
CN-116807990-A Esomeprazole magnesium enteric capsule and preparation method thereof 桂林华信制药有限公司 2023-09-29 — — CN disclosed
CN-116585283-A Lansoprazole enteric capsule and preparation method thereof 桂林华信制药有限公司 2023-08-15 — — CN disclosed
EP-0684259-B1 L-lysyl-glycyl-L-histidine and therapeutic agent for wound healing containing the same HOECHST JAPAN (JP) 1999-11-17 — — EP disclosed
US-5591711-A LYSINE-GLYCINE-HISTIDINE TRIPEPTIDE, FIBROBLAST PROLIFERATION HOECHST JAPAN LIMITED (JP) 1997-01-07 — — US disclosed
EP-0684259-A1 L-lysyl-glycyl-L-histidine and therapeutic agent for wound healing containing the same HOECHST JAPAN LIMITED (JP) 1995-11-29 — — EP disclosed
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