Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RARB | P10826 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436678 | 0.95 | RAB9A (0.50) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9625879 | 0.87 | RARB (0.50) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL8432006 | 0.85 | RARB (0.46) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL8433914 | 0.85 | RARB (0.46) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9184595 | 0.83 | NPC1 (0.69) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9330768 | 0.83 | NPC1 (0.69) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL8436583 | 0.83 | RARB (0.46) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL6251962 | 0.81 | RAB9A (0.45) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL10468952 | 0.81 | NPC1 (0.52) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL10469839 | 0.81 | NPC1 (0.52) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499221-B1 | Optically active compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1999-12-08 | — | — | EP | disclosed |
| US-5281362-A | Ferroelectric liquid crystals for optics | CANON KABUSHIKI KAISHA (JP) | 1994-01-25 | — | — | US | disclosed |
| EP-0499221-A1 | Optically active compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1992-08-19 | — | — | EP | disclosed |