Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521032 | 0.80 | TDP1 (0.30) | — | |
| SCHEMBL9791500 | 0.75 | KDM4E (0.30) | KDM4E | |
| SCHEMBL9875892 | 0.74 | ALDH1A1 (0.37) | ALDH1A1TSHRHTTKDM4E | |
| SCHEMBL27609624 | 0.72 | ALDH1A1 (0.40) | ALDH1A1KDM4E | |
| SCHEMBL27442525 | 0.72 | ALDH1A1 (0.35) | CHEK1ALDH1A1HTTKDM4E | |
| SCHEMBL13698320 | 0.72 | — | — | |
| SCHEMBL11322989 | 0.72 | ALDH1A1 (0.33) | ALDH1A1KDM4E | |
| SCHEMBL5187756 | 0.70 | KDM4E (0.40) | ALDH1A1KDM4E | |
| SCHEMBL3654750 | 0.69 | ALDH1A1 (0.34) | ALDH1A1TSHRHTTKDM4E | |
| SCHEMBL9791520 | 0.69 | TLR8 (0.33) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847749-B1 | Use of diiminoisoindoline or 3-aminoisoindolone derivatives for the dyeing of keratinic fibers and compositions containing them | OREAL (FR) | 1999-12-01 | — | — | EP | disclosed |
| EP-0847749-A1 | Use of diiminoisoindoline or 3-aminoisoindolone derivatives for the dyeing of keratinic fibers and compositions containing them | L'OREAL (FR) | 1998-06-17 | — | — | EP | disclosed |