SCHEMBL84327

SCHEMBL84327

Cc1ccc2nc(C)sc2c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.66
RAB9A P51151 4/20 0.66
MAPT P10636 4/20 0.66
NPC1 O15118 4/20 0.61
ALDH1A1 P00352 2/20 0.61
TP53 P04637 1/20 0.61
PKM P14618 1/20 0.61
HPGD P15428 1/20 0.61
HSD17B10 Q99714 1/20 0.61
GAA P10253 2/20 0.57
TDP1 Q9NUW8 2/20 0.56
HTT P42858 2/20 0.56
APP P05067 5/20 0.54
KDM4E B2RXH2 2/20 0.54
GLA P06280 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
KMT2A Q03164 3/20 0.54
MEN1 O00255 2/20 0.54
LMNA P02545 2/20 0.54
RXFP1 Q9HBX9 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30542465 1.00 SMN1; SMN2 (0.66) SMN1; SMN2RAB9AMAPTNPC1ALDH1A1
SCHEMBL13444809 0.83 MAPT (0.69) SMN1; SMN2RAB9AMAPTNPC1ALDH1A1
SCHEMBL92781 0.83 SMN1; SMN2 (0.61) SMN1; SMN2RAB9AMAPTNPC1ALDH1A1
Ethylbenzene SCHEMBL11678150 0.82 TDP1 (0.51) SMN1; SMN2RAB9AMAPTNPC1ALDH1A1
SCHEMBL1638573 0.81 RAB9A (0.63) SMN1; SMN2RAB9AMAPTNPC1ALDH1A1
Bromide SCHEMBL10996884 0.81 SMN1; SMN2 (0.59) SMN1; SMN2RAB9AMAPTNPC1ALDH1A1
SCHEMBL10271447 0.80 SMN1; SMN2 (0.67) SMN1; SMN2RAB9AMAPTNPC1ALDH1A1
SCHEMBL25165513 0.79 RAB9A (0.61) SMN1; SMN2RAB9AMAPTNPC1ALDH1A1
SCHEMBL2231243 0.79 RAB9A (0.61) SMN1; SMN2RAB9AMAPTNPC1ALDH1A1
SCHEMBL8470440 0.79 SMN1; SMN2 (0.61) SMN1; SMN2RAB9AMAPTNPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 738 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118048155-A Titanium nitride etching liquid, preparation method, application and cleaning method thereof 浙江奥首材料科技有限公司 2024-05-17 CN claimed
CN-113045993-A Polishing solution for processing ultra-smooth low-damage bearing steel surface and application thereof 西南交通大学 2021-06-29 CN claimed
US-10655015-B2 Tire crumb-based bitumen polymer for producing a lower viscosity asphalt with improved tolerance to high temperatures Argopro Group LLC (US) 2020-05-19 US claimed
US-20200095424-A1 TIRE CRUMB-BASED BITUMEN POLYMER FOR PRODUCING A LOWER VISCOSITY ASPHALT WITH IMPROVED TOLERANCE TO HIGH TEMPERATURES Argopro Group LLC 2020-03-26 US claimed
CN-107523088-B A kind of asymmetric side's acid cyanines probe and its preparation method and application based on cyano 常州大学 2019-06-04 CN claimed
CN-107523088-A A kind of asymmetric side's acid cyanines probe based on cyano group and its preparation method and application 常州大学 2017-12-29 CN claimed
EP-4661058-A1 CLEANING AGENT COMPOSITION AND CLEANING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-12-10 EP disclosed
US-20250084351-A1 PROCESSING SOLUTION, METHOD FOR PROCESSING SUBSTRATE, AND METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE TOKYO OHKA KOGYO CO., LTD. (JP) 2025-03-13 US disclosed
WO-2024162320-A1 CLEANING AGENT COMPOSITION AND CLEANING METHOD 信越化学工業株式会社 2024-08-08 WO disclosed
WO-2024142789-A1 GOLD ELECTROPLATING SOLUTION AND METHOD FOR PRODUCING GOLD-ELECTROPLATED COATING 日本高純度化学株式会社 2024-07-04 WO disclosed
US-12023324-B2 Controlled release formulations of riluzole and their uses ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2024-07-02 US disclosed
CN-118048155-A Titanium nitride etching liquid, preparation method, application and cleaning method thereof 浙江奥首材料科技有限公司 2024-05-17 CN disclosed
CN-117843557-A Large Stokes displacement nucleic acid probe, preparation method and application thereof 大连理工大学 2024-04-09 CN disclosed
US-6368864-B1 Dyes and methods of reticulocyte enumeration COULTER INTERNATIONAL CORP. 2002-04-09 US disclosed
US-20020037589-A1 Dyes and methods of detection of nucleic acid in immature red blood cells COULTER INTERNATIONAL CORP. 2002-03-28 US disclosed
WO-2001086264-A1 DYES AND METHODS OF DETECTION OF NUCLEIC ACID IN IMMATURE RED BLOOD CELLS COULTER INTERNATIONAL CORP. (US) 2001-11-15 WO disclosed
US-5604088-A METHINE DYE SENSITIZERS; LOW CALCIUM CONTENT; EXCELLENT PROCESS STABILITY; FORMS LESS STREAKS IN CONTINUOUS PROCESSING FUJI PHOTO FILM CO., LTD. (JP) 1997-02-18 US disclosed
US-5561039-A SUPPORTED SILVER HALIDE LAYER SPECTRALLY SENSITIZED BY A RED-SENSITIVE METHINE BENZOTHIAZOLE DYE AND CONTAINING A THIOSULFONATE AND SULFINATE; ANTIFOGGING AGENTS; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1996-10-01 US disclosed
EP-0615159-A1 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1994-09-14 EP disclosed
US-4539408-A Process for the preparation of sulphoalkyl quaternary salts AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1985-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12023324-B2 Controlled release formulations of riluzole and their uses SMN1; SMN2, IL2, NEFM SMN1; SMN2 1/4885RAB9A 307/4885MAPT 200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.