Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 5/20 | 0.45 |
| ▸ | SSTR5 | P35346 | 5/20 | 0.45 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 9/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.43 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431391 | 0.89 | TLR4 (0.42) | SSTR3SSTR5SSTR2MCHR1 | |
| SCHEMBL8431686 | 0.88 | L3MBTL1 (0.40) | SSTR3SSTR5SSTR2MCHR1SSTR4 | |
| SCHEMBL8432989 | 0.83 | TLR4 (0.40) | MCHR1L3MBTL1 | |
| SCHEMBL8436537 | 0.83 | TLR4 (0.40) | MCHR1L3MBTL1 | |
| SCHEMBL8432987 | 0.83 | TLR4 (0.40) | MCHR1L3MBTL1 | |
| SCHEMBL8436534 | 0.82 | L3MBTL1 (0.40) | MCHR1L3MBTL1 | |
| SCHEMBL8433665 | 0.81 | TLR4 (0.44) | L3MBTL1 | |
| SCHEMBL8435522 | 0.81 | TLR4 (0.44) | L3MBTL1 | |
| SCHEMBL8434486 | 0.81 | TLR4 (0.44) | L3MBTL1 | |
| SCHEMBL8431677 | 0.81 | TLR4 (0.44) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36385-E | TREATMENT OF TUMORS, ENHANCING IMMUNITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| US-4925929-A | ANTITUMOR AGENTS | ONO PHARMACEUTICAL CO. LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0226381-A2 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-06-24 | — | — | EP | disclosed |