SCHEMBL8433121

SCHEMBL8433121

C=C(C)C(=O)N(C(=O)OC(C)CC)C(=O)C(=C)C

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11747348 0.80 TSHR (0.33) TSHR
SCHEMBL1863804 0.80 TSHR (0.33) TSHR
SCHEMBL33467 0.74 TSHR (0.48) TSHR
SCHEMBL28322415 0.72 TSHR (0.47) TSHR
SCHEMBL28322566 0.72 TSHR (0.47) TSHR
SCHEMBL27805092 0.72 TSHR (0.47) TSHR
SCHEMBL14759451 0.71 CHRNB2 (0.41) TSHR
SCHEMBL8455989 0.71 CHRNB2 (0.41) TSHR
SCHEMBL11748204 0.71 TSHR (0.32) TSHR
SCHEMBL10369020 0.70 MAPT (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5892100-A DEHYDROHALOGENATION BY REACTION OF UNSATURATED ACID HALIDES WITH CARBAMATE IN THE PRESENCE OF HINDERED AMINE NIPPON PAINT CO., LTD. (JP) 1999-04-06 US disclosed
EP-0827953-A2 Method for producing N-acyl carbamate Nippon Paint Co., Ltd. (JP) 1998-03-11 EP disclosed