SCHEMBL8433130

SCHEMBL8433130

CCc1cc(C=O)c(O)c(C=O)c1

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 14/20 0.58
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
CDK1 P06493 1/20 0.41
PIM1 P11309 1/20 0.38
TYR P14679 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8653663 0.90 ERN1 (0.47) ERN1LMNAMAPTCDK1PIM1
SCHEMBL3966884 0.90 ERN1 (0.47) ERN1LMNAMAPTCDK1
SCHEMBL5647563 0.88 ERN1 (0.50) ERN1LMNAMAPTCDK1
SCHEMBL5884087 0.86 ERN1 (0.58) ERN1LMNAMAPTCDK1
SCHEMBL5883309 0.86 ERN1 (0.58) ERN1LMNAMAPTCDK1
SCHEMBL18218317 0.85 KDM4E (0.43) ERN1LMNAMAPTCDK1
SCHEMBL5644612 0.83 LMNA (0.69) ERN1LMNAMAPT
SCHEMBL5882422 0.83 ERN1 (0.41) ERN1LMNAMAPTCDK1
SCHEMBL28526519 0.83 ERN1 (0.41) ERN1LMNAMAPTCDK1
SCHEMBL10711741 0.82 ERN1 (0.40) ERN1LMNAMAPTCDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114395233-B Degradable plastic and preparation method thereof 清华大学 2022-10-25 CN disclosed
CN-114395233-A Degradable plastic and preparation method thereof 清华大学 2022-04-26 CN disclosed
EP-0662486-B1 AROMATIC POLYIMINES AND AROMATIC OLIGOIMINES AND PROCESS FOR PRODUCING THE SAME ARAKAWA CHEM IND (JP) 1999-12-08 EP disclosed
US-5512641-A RECURRING UNIT COMPOSED OF AN AROMATIC DIALDEHYDE HAVING A PHENOLIC HYDROXYL GROUP AND AN AROMATIC DIAMINE ARAKAWA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-04-30 US disclosed
EP-0662486-A1 AROMATIC POLYIMINE, PROCESS FOR PRODUCING THE SAME, AROMATIC POLYIMINE OLIGOMER USED FOR PRODUCING SAID POLYIMINE, AND PROCESS FOR PRODUCING SAID OLIGOMER ARAKAWA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1995-07-12 EP disclosed