SCHEMBL8433131

SCHEMBL8433131

[CH]=CCCCCCCCCCCCCCCCCCCCO

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 1/20 0.38
GPR84 Q9NQS5 1/20 0.33
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3176431 1.00 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL4873474 1.00 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL4872961 1.00 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL3331317 1.00 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL3170404 1.00
SCHEMBL8433135 1.00 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL3046759 1.00 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL8433677 1.00 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL4874291 1.00 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL3174948 1.00 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5929283-A HYDROXY AMINES; LOW IN IRRITATIVENESS TO THE SKIN AND HAIR AND EXCELLENT IN FOAMABILITY, AND CAN GIVE A PLEASANT FEELING TO THE USER'S SKIN KAO CORPORATION (JP) 1999-07-27 US disclosed
US-5885955-A MILDNESS, LATHERABILITY, EMULSION STABILITY KAO CORPORATION (JP) 1999-03-23 US disclosed
US-5801270-A Amine derivative and detergent composition containing the same KAO CORPORATION (JP) 1998-09-01 US disclosed
EP-0740651-B1 AMINE DERIVATIVE AND DETERGENT COMPOSITION CONTAINING THE SAME KAO CORP (JP) 1998-08-12 EP disclosed
US-5756784-A LATHERABILITY; EMULSION STABILITY KAO CORPORATION (JP) 1998-05-26 US disclosed
EP-0740651-A1 AMINE DERIVATIVE AND DETERGENT COMPOSITION CONTAINING THE SAME Kao Corporation (JP) 1996-11-06 EP disclosed
WO-1995016664-A1 AMINE DERIVATIVE AND DETERGENT COMPOSITION CONTAINING THE SAME KAO CORPORATION (JP) 1995-06-22 WO disclosed