SCHEMBL8433156

SCHEMBL8433156

[CH2]CC(=O)NC(C)C(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
SIGMAR1 Q99720 1/20 0.42
TAS1R3 Q7RTX0 3/20 0.39
TAS1R1 Q7RTX1 3/20 0.39
TAS1R2 Q8TE23 3/20 0.39
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
POLB P06746 2/20 0.37
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HPGD P15428 2/20 0.36
ALDH1A1 P00352 1/20 0.35
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
PIK3CD O00329 1/20 0.32
HRH3 Q9Y5N1 2/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16298847 0.79 CYP2C9 (0.46) CYP3A4CYP2C9CYP2C19SIGMAR1TAS1R3
SCHEMBL31483043 0.79 CYP2C9 (0.46) CYP3A4CYP2C9CYP2C19SIGMAR1TAS1R3
SCHEMBL15116375 0.77 CYP3A4 (0.44) CYP3A4CYP2C9CYP2C19SIGMAR1TAS1R3
SCHEMBL1018454 0.77 CYP3A4 (0.44) CYP3A4CYP2C9CYP2C19SIGMAR1TAS1R3
SCHEMBL13826479 0.77 CYP3A4 (0.44) CYP3A4CYP2C9CYP2C19SIGMAR1TAS1R3
SCHEMBL1018455 0.77 CYP3A4 (0.44) CYP3A4CYP2C9CYP2C19SIGMAR1TAS1R3
SCHEMBL8438615 0.76 SMN1; SMN2 (0.40) TAS1R3TAS1R1TAS1R2MEN1KMT2A
SCHEMBL20056731 0.76 CYP3A4 (0.43) CYP3A4CYP2C9CYP2C19SIGMAR1TAS1R3
SCHEMBL2364047 0.76 CYP3A4 (0.43) CYP3A4CYP2C9CYP2C19SIGMAR1TAS1R3
SCHEMBL19988829 0.76 HDAC3 (0.44) CYP3A4CYP2C9CYP2C19SIGMAR1TAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0777658-B1 SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS BASF AG (DE) 1999-12-15 EP disclosed
US-5885934-A HERBICIDES OR FOR THE DESICCATION/DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 1999-03-23 US disclosed
EP-0777658-A1 SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS BASF AKTIENGESELLSCHAFT (DE) 1997-06-11 EP disclosed
WO-1996005179-A1 SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS BASF AKTIENGESELLSCHAFT (DE) 1996-02-22 WO disclosed