⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161586 | 1.00 | — | — | |
| SCHEMBL3742130 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL7710922 | 0.97 | — | — | |
| Ethylene Glycol SCHEMBL27658842 | 0.92 | ENPEP (0.52) | — | |
| Ethylene Glycol SCHEMBL1171186 | 0.92 | ENPEP (0.52) | — | |
| Butane SCHEMBL22497640 | 0.89 | ENPEP (0.50) | — | |
| Acetaldehyde SCHEMBL28888848 | 0.89 | ENPEP (0.50) | — | |
| 1,4-Butanediol SCHEMBL4458925 | 0.87 | ENPEP (0.48) | — | |
| Propylene Glycol SCHEMBL1171159 | 0.87 | ENPEP (0.48) | — | |
| SCHEMBL1170965 | 0.85 | ENPEP (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103156833-B | (R) purposes of the mercaptopropionic acid of 2 methyl 3 in the medicine for suppressing production NDM 1 drug-resistant bacteria activity is prepared | 天津市国际生物医药联合研究院 | 2017-07-14 | — | — | CN | claimed |
| CN-103156833-A | Application of (R)-2-methyl-3-mercaptopropionic acid in inhibiting NDM-1 | TIANJIN INT JOINT ACADEMY BIOTECHNOLOGY & MEDICINE | 2013-06-19 | — | — | CN | claimed |
| US-20180002373-A1 | Amino Acid and Peptide Conjugates and Uses Thereof | AUCKLAND UNISERVICES LIMITED (NZ) | 2018-01-04 | — | — | US | disclosed |
| EP-2778234-B1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORP (US) | 2017-09-27 | — | — | EP | disclosed |
| US-20170258923-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | PURDUE RESEARCH FOUNDATION | 2017-09-14 | — | — | US | disclosed |
| CN-103156833-B | (R) purposes of the mercaptopropionic acid of 2 methyl 3 in the medicine for suppressing production NDM 1 drug-resistant bacteria activity is prepared | 天津市国际生物医药联合研究院 | 2017-07-14 | — | — | CN | disclosed |
| US-20170095554-A1 | AMINO ACID AND PEPTIDE CONJUGATES AND CONJUGATION PROCESS | AUCKLAND UNISERVICES LIMITED (NZ) | 2017-04-06 | — | — | US | disclosed |
| US-20160304459-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND APPLICATION THEREFOR | TOKYO UNIVERSITY OF PHARMACY & LIFE SCIENCES (JP) | 2016-10-20 | — | — | US | disclosed |
| US-9193681-B1 | Propionic acids, propionic acid esters, and related compounds | PROMENTIS PHARMACEUTICALS, INC. (US) | 2015-11-24 | — | — | US | disclosed |
| US-20150175559-A1 | CYSTEINE AND CYSTINE PRODRUGS TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS | MARQUETTE UNIVERSITY (US) | 2015-06-25 | — | — | US | disclosed |
| US-9056141-B2 | Thiol-ene click chemistry for drug conjugates | SYNCHEM, INC. (US) | 2015-06-16 | — | — | US | disclosed |
| US-20090306337-A1 | Pegylated, Extended Insulins | NOVO NORDISK A/S (DK) | 2009-12-10 | — | — | US | disclosed |
| CN-101594886-A | Radiographical moieties coupled to peptidase-binding moieties for imaging tissues and organs expressing peptidases | MOLECULAR INSIGHT PHARM INC (US) | 2009-12-02 | — | — | CN | disclosed |
| US-20090098083-A1 | CONJUGATE ADDITION REACTIONS FOR THE CONTROLLED DELIVERY OF PHARMACEUTICALLY ACTIVE COMPOUNDS | UNIVERSITAT ZURICH (CH) | 2009-04-16 | — | — | US | disclosed |
| US-7425635-B2 | Prodrugs and conjugates of thiol- and selenol-containing compounds and methods of use thereof | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2008-09-16 | — | — | US | disclosed |
| US-20060039861-A1 | Peptide-based multimeric targeted contrast agents | EPIX MEDICAL, INC., A DELAWARE CORPORATION | 2006-02-23 | — | — | US | disclosed |
| US-5534427-A | GENE EXPRESSION | E. R. SQUIBB & SONS, INC. (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0480708-B1 | Hydroxyalkylquinoline ether acids as leukotriene antagonists | MERCK FROSST CANADA INC (CA) | 1995-10-11 | — | — | EP | disclosed |
| US-5266568-A | Hydroxyalkylquinoline ether acids as leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1993-11-30 | — | — | US | disclosed |
| EP-0480708-A2 | Hydroxyalkylquinoline ether acids as leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1992-04-15 | — | — | EP | disclosed |