Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 6/20 | 0.87 |
| ▸ | IKBKB | O14920 | 4/20 | 0.87 |
| ▸ | RARG | P13631 | 9/20 | 0.47 |
| ▸ | RARB | P10826 | 4/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535785 | 0.93 | RARA (1.00) | RARAIKBKBRARGRARBHDAC11 | |
| SCHEMBL6570378 | 0.93 | RARA (1.00) | RARAIKBKBRARGRARBHDAC11 | |
| SCHEMBL8433867 | 0.91 | RARA (0.74) | RARAIKBKBRARGRARB | |
| SCHEMBL8397886 | 0.88 | RARA (0.66) | RARAIKBKBRARGRARB | |
| SCHEMBL29999156 | 0.86 | RARA (0.88) | RARAIKBKBRARGRARBHDAC11 | |
| SCHEMBL8434108 | 0.86 | RARA (0.66) | RARAIKBKBRARGRARB | |
| SCHEMBL8431874 | 0.86 | RARA (0.66) | RARAIKBKBRARGRARB | |
| SCHEMBL8428596 | 0.86 | IKBKB (0.87) | RARAIKBKBRARGRARBHDAC11 | |
| SCHEMBL5887966 | 0.85 | RARA (0.83) | RARAIKBKBRARGRARBHDAC11 | |
| SCHEMBL8431943 | 0.85 | RARA (0.64) | RARAIKBKBRARGRARBHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776881-B1 | Bi-aromatic compounds comprising an adamantyl group in para-position, pharmaceutical and cosmetic compositions containing them and their utilization | CIRD GALDERMA (FR) | 1999-12-08 | — | — | EP | disclosed |
| EP-0776881-A1 | Bi-aromatic compounds comprising an adamantyl group in para-position, pharmaceutical and cosmetic compositions containing them and their utilization | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1997-06-04 | — | — | EP | disclosed |