SCHEMBL8433529

SCHEMBL8433529

CCC(C)Nc1cccc(Sc2ccccc2)c1NC(C)CC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 8/20 0.39
ALDH1A1 P00352 5/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
BLM P54132 1/20 0.38
LMNA P02545 3/20 0.38
HPGD P15428 1/20 0.38
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 4/20 0.37
MAPT P10636 1/20 0.37
CYP3A4 P08684 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
TP53 P04637 1/20 0.37
HSP90AA1 P07900 1/20 0.37
THRB P10828 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
CASP1 P29466 1/20 0.37
HIF1A Q16665 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8438043 0.89 L3MBTL1 (0.38) L3MBTL1ALDH1A1KMT2AMEN1BLM
SCHEMBL8438496 0.86 CACNA2D1 (0.36) L3MBTL1ALDH1A1KMT2AMEN1BLM
SCHEMBL8436657 0.85 CACNA2D1 (0.38) L3MBTL1ALDH1A1KMT2AMEN1BLM
SCHEMBL8433907 0.84 CACNA2D1 (0.37) L3MBTL1ALDH1A1KMT2AMEN1BLM
SCHEMBL8433988 0.84 CACNA2D1 (0.37) L3MBTL1ALDH1A1KMT2AMEN1BLM
SCHEMBL8433518 0.84 CACNA2D1 (0.37) L3MBTL1ALDH1A1KMT2AMEN1BLM
SCHEMBL8436349 0.84 CACNA2D1 (0.37) L3MBTL1ALDH1A1KMT2AMEN1BLM
SCHEMBL8439690 0.84 CACNA2D1 (0.37) L3MBTL1ALDH1A1KMT2AMEN1BLM
SCHEMBL8433384 0.84 CACNA2D1 (0.37) L3MBTL1ALDH1A1KMT2AMEN1BLM
SCHEMBL8434141 0.84 CACNA2D1 (0.37) L3MBTL1ALDH1A1KMT2AMEN1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5922654-A TWO OR MORE ORGANOMETALLIC COMPOUNDS WHERE THE METAL IS A TRANSITION METAL OR SEMIMETAL, OR ZINC; FOR EXAMPLE, ZINC DIALKYLDITHIOPHOSPHATE, OR NICKEL DIALKYLDITHIOCARBAMATE; HIGHER LOAD BEARING PROPERTIES, HIGH TEMPERATURE PERFORMANCE NSK LTD. (JP) 1999-07-13 US disclosed
US-4394279-A Antioxidant combinations of sulfur containing molybdenum complexes and aromatic amine compounds for lubricating oils CHEVRON RESEARCH COMPANY (US) 1983-07-19 US disclosed
US-4370246-A Antioxidant combinations of molybdenum complexes and aromatic amine compounds CHEVRON RESEARCH COMPANY (US) 1983-01-25 US disclosed