Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 6/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 5/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.35 |
| ▸ | TLR4 | O00206 | 2/20 | 0.35 |
| ▸ | LY96 | Q9Y6Y9 | 2/20 | 0.35 |
| ▸ | SELP | P16109 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8433590 | 0.95 | TLR4 (0.37) | SSTR5SSTR3SSTR2SSTR1SSTR4 | |
| SCHEMBL8434878 | 0.90 | TLR4 (0.43) | SMPD1TLR4LY96SELP | |
| SCHEMBL8434876 | 0.90 | TLR4 (0.43) | SMPD1TLR4LY96SELP | |
| SCHEMBL10417891 | 0.85 | CA1 (0.41) | SSTR5SSTR3SSTR2CNR2SMPD1 | |
| SCHEMBL8433583 | 0.83 | CNR2 (0.37) | SSTR5SSTR3SSTR2SSTR1SSTR4 | |
| SCHEMBL10418866 | 0.82 | CA1 (0.42) | SSTR5SSTR3SSTR2CNR2SMPD1 | |
| SCHEMBL10418864 | 0.82 | CA1 (0.42) | SSTR5SSTR3SSTR2CNR2SMPD1 | |
| SCHEMBL10417644 | 0.81 | TLR4 (0.47) | SSTR5SSTR3SSTR2SSTR1SSTR4 | |
| SCHEMBL7454562 | 0.81 | TLR4 (0.51) | SSTR5SSTR3SSTR2SSTR1SSTR4 | |
| SCHEMBL10419171 | 0.80 | SMPD1 (0.41) | CNR2SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36385-E | TREATMENT OF TUMORS, ENHANCING IMMUNITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0288888-B1 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-4925929-A | ANTITUMOR AGENTS | ONO PHARMACEUTICAL CO. LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0288888-A2 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |