Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 10/20 | 0.43 |
| ▸ | LY96 | Q9Y6Y9 | 6/20 | 0.43 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.43 |
| ▸ | SELP | P16109 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SELE | P16581 | 1/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434878 | 1.00 | TLR4 (0.43) | TLR4LY96LGALS8SELPCA1 | |
| SCHEMBL10418866 | 0.92 | CA1 (0.42) | LGALS8SELPCA1CA2CA9 | |
| SCHEMBL10418864 | 0.92 | CA1 (0.42) | LGALS8SELPCA1CA2CA9 | |
| SCHEMBL8433586 | 0.90 | SSTR5 (0.37) | TLR4LY96SELPSMPD1 | |
| SCHEMBL10419818 | 0.88 | TLR4 (0.47) | TLR4LY96LGALS8CA1CA2 | |
| SCHEMBL10419817 | 0.88 | TLR4 (0.47) | TLR4LY96LGALS8CA1CA2 | |
| SCHEMBL10417891 | 0.87 | CA1 (0.41) | LGALS8SELPCA1CA2CA9 | |
| SCHEMBL10961054 | 0.85 | TLR4 (0.58) | TLR4LY96LGALS8SELP | |
| SCHEMBL10961052 | 0.85 | TLR4 (0.58) | TLR4LY96LGALS8SELP | |
| SCHEMBL8433590 | 0.84 | TLR4 (0.37) | TLR4LY96SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36385-E | TREATMENT OF TUMORS, ENHANCING IMMUNITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0288888-B1 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-4925929-A | ANTITUMOR AGENTS | ONO PHARMACEUTICAL CO. LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0288888-A2 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |