Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8435682 | 0.99 | PTGS1 (0.33) | PTGS1PTGS2IDH1 | |
| SCHEMBL8433420 | 0.82 | IDH1 (0.42) | IDH1 | |
| Hydrochloric Acid SCHEMBL8434597 | 0.81 | IDH1 (0.41) | IDH1 | |
| SCHEMBL8438545 | 0.78 | SMN1; SMN2 (0.49) | — | |
| Hydrochloric Acid SCHEMBL8437554 | 0.77 | SMN1; SMN2 (0.48) | — | |
| Hydrochloric Acid SCHEMBL8495697 | 0.76 | RAB9A (0.44) | IDH1 | |
| SCHEMBL8432982 | 0.74 | TAAR1 (0.45) | — | |
| SCHEMBL8434690 | 0.74 | PRSS1 (0.47) | — | |
| Hydrochloric Acid SCHEMBL8435752 | 0.74 | TAAR1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL8435334 | 0.73 | IDH1 (0.33) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874585-A | TREATMENT AND/OR PREVENTION OF ELASTASE-MEDIATED PROBLEMS SUCH AS ARTHRITIS, PERIODONTAL DISEASE, GLOMERULONEPHRITIS, DERMATITIS, PSORIASIS, CYSTIC FIBROSIS, CHRONIC BRONCHITIS, ALZHEIMER'S DISEASE | CORTECH, INC. (US) | 1999-02-23 | — | — | US | disclosed |