Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | TACR2 | P21452 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TST | Q16762 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5600659 | 1.00 | ALDH1A1 (0.56) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL8372837 | 1.00 | ALDH1A1 (0.56) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL28340889 | 1.00 | ALDH1A1 (0.56) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL317709 | 1.00 | ALDH1A1 (0.56) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL10348762 | 0.98 | ALDH1A1 (0.53) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL28044881 | 0.94 | ALDH1A1 (0.50) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL9651434 | 0.94 | ALDH1A1 (0.50) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL28378039 | 0.93 | CA1 (0.48) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL7952171 | 0.90 | ESR1 (0.50) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL8802114 | 0.89 | ALDH1A1 (0.56) | ALDH1A1ESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090491-A1 | PHENOL-FREE PHOSPHITES DERIVATIVES AND PREPARATION THEREOF | CHANG CHUN PETROCHEMICAL CO., LTD. (TW) | 2013-04-11 | — | — | US | disclosed |
| EP-0450208-B1 | Lubricant compositions and additives therefor | ETHYL PETROLEUM ADDITIVES LTD (GB) | 1999-12-01 | — | — | EP | disclosed |
| EP-0391653-B1 | Lubricant compositions | ETHYL PETROLEUM ADDITIVES LTD (GB) | 1994-03-02 | — | — | EP | disclosed |
| EP-0375324-B1 | Production of phosphorothioate salts | ETHYL PETROLEUM ADDITIVES LTD (GB) | 1994-02-02 | — | — | EP | disclosed |
| US-5210261-A | Antiwear additives for lubricants; reacting sulfur, amine, phosphite ester | ETHYL PETROLEUM ADDITIVES, LTD. (GB) | 1993-05-11 | — | — | US | disclosed |
| US-5126064-A | For noise reduction in limited slip differentials | ETHYL PETROLEUM ADDITIVES, LTD. (GB) | 1992-06-30 | — | — | US | disclosed |
| EP-0399764-B1 | LUBRICANT COMPOSITIONS | ETHYL PETROLEUM ADDITIVES LIMITED (GB) | 1992-03-25 | — | — | EP | disclosed |
| EP-0399764-A1 | Lubricant compositions | ETHYL PETROLEUM ADDITIVES LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |
| EP-0391653-A2 | Lubricant compositions | ETHYL PETROLEUM ADDITIVES LIMITED (GB) | 1990-10-10 | — | — | EP | disclosed |
| EP-0375324-A1 | Production of phosphorothioate salts | ETHYL PETROLEUM ADDITIVES LIMITED (GB) | 1990-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090491-A1 | PHENOL-FREE PHOSPHITES DERIVATIVES AND PREPARATION THEREOF | PHOSPHO1, PPA1, PLCG2 | ALDH1A1 2808/4885ESR1 69/4885ADRA2A 3739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.