Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 14/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 14/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 14/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 14/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434716 | 0.89 | PRSS1 (0.56) | PRSS1PRSS2PRSS3TPSAB1ATM | |
| SCHEMBL8435688 | 0.88 | PRSS1 (0.43) | PRSS1PRSS2PRSS3TPSAB1ATM | |
| SCHEMBL8436580 | 0.84 | ATM (0.50) | PRSS1PRSS2PRSS3TPSAB1ATM | |
| SCHEMBL8437485 | 0.83 | PRSS1 (0.61) | PRSS1PRSS2PRSS3TPSAB1ATM | |
| SCHEMBL8433513 | 0.83 | PRSS1 (0.48) | PRSS1PRSS2PRSS3TPSAB1ATM | |
| SCHEMBL8433200 | 0.82 | ATM (0.48) | PRSS1PRSS2PRSS3TPSAB1ATM | |
| SCHEMBL8435655 | 0.82 | ATM (0.51) | PRSS1PRSS2PRSS3TPSAB1ATM | |
| SCHEMBL8434690 | 0.82 | PRSS1 (0.47) | PRSS1PRSS2PRSS3TPSAB1ATM | |
| SCHEMBL8434784 | 0.82 | PRSS1 (0.46) | PRSS1PRSS2PRSS3TPSAB1ATM | |
| SCHEMBL8433402 | 0.81 | PRSS1 (0.52) | PRSS1PRSS2PRSS3TPSAB1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874585-A | TREATMENT AND/OR PREVENTION OF ELASTASE-MEDIATED PROBLEMS SUCH AS ARTHRITIS, PERIODONTAL DISEASE, GLOMERULONEPHRITIS, DERMATITIS, PSORIASIS, CYSTIC FIBROSIS, CHRONIC BRONCHITIS, ALZHEIMER'S DISEASE | CORTECH, INC. (US) | 1999-02-23 | — | — | US | disclosed |