SCHEMBL8435688

SCHEMBL8435688

CC(=O)OC(c1noc(CCCc2ccccc2)n1)[C@@H](NC(=O)OCc1ccccc1)C(C)C

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 14/20 0.43
PRSS2 P07478 14/20 0.43
PRSS3 P35030 14/20 0.43
TPSAB1 Q15661 14/20 0.43
ATM Q13315 1/20 0.42
CA2 P00918 1/20 0.39
CA5A P35218 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8433741 0.90 PRSS1 (0.52) PRSS1PRSS2PRSS3TPSAB1ATM
SCHEMBL8433712 0.88 PRSS1 (0.46) PRSS1PRSS2PRSS3TPSAB1ATM
SCHEMBL8433073 0.86 ATM (0.46) PRSS1PRSS2PRSS3TPSAB1ATM
SCHEMBL8436756 0.84 PRSS1 (0.57) PRSS1PRSS2PRSS3TPSAB1ATM
SCHEMBL8433316 0.84 PRSS1 (0.45) PRSS1PRSS2PRSS3TPSAB1ATM
SCHEMBL8432904 0.84 ATM (0.44) PRSS1PRSS2PRSS3TPSAB1ATM
SCHEMBL8437486 0.84 ATM (0.47) PRSS1PRSS2PRSS3TPSAB1ATM
SCHEMBL8435264 0.84 PRSS1 (0.43) PRSS1PRSS2PRSS3TPSAB1ATM
SCHEMBL8433174 0.84 PRSS1 (0.44) PRSS1PRSS2PRSS3TPSAB1ATM
SCHEMBL8434777 0.83 PRSS1 (0.49) PRSS1PRSS2PRSS3TPSAB1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3313910-A1 POLYURETHANE SYSTEMS FOR LAYER STRUCTURES IN WIND TURBINES Covestro Deutschland AG (DE) 2018-05-02 EP disclosed
US-5936034-A MIXTURE CONTAINING UNSATURATED POLYESTER (FROM DIOL, POLYCARBOXYLIC ACID AND REACTIVE CURING MONOMER), PREPOLYMER CONTAINING ISOCYANATE GROUPS, CURING SYSTEM OF CATALYST, ACCELERATOR AND TRIMERIZATION CATALYST, ADDITIVES ECP ENICHEM POLIMERI NETHERLANDS B.V. (NL) 1999-08-10 US disclosed
US-5904986-A APPLYING UNSATURATED POLYESTER, POLYISOCYANATE PREPOLYMER, CURING AGENT, ACCELERATOR, TRIMERIZATION CATALYST, POLYURETHANE BACKING; CURING; HIGH SPEED PROCESSING; HEAT RESISTANCE, BONDING STRENGTH ECP ENICHEM POLIMERI NETHERLANDS B.V. (NL) 1999-05-18 US disclosed
US-5874585-A TREATMENT AND/OR PREVENTION OF ELASTASE-MEDIATED PROBLEMS SUCH AS ARTHRITIS, PERIODONTAL DISEASE, GLOMERULONEPHRITIS, DERMATITIS, PSORIASIS, CYSTIC FIBROSIS, CHRONIC BRONCHITIS, ALZHEIMER'S DISEASE CORTECH, INC. (US) 1999-02-23 US disclosed
EP-0714743-A1 Process for the production of gel-coated articles ECP Enichem Polimeri Netherlands B.V. (NL) 1996-06-05 EP disclosed