Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 17/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430684 | 0.90 | LTB4R (0.51) | LTB4RALDH1A1SMN1; SMN2 | |
| SCHEMBL8430609 | 0.88 | LTB4R (0.60) | LTB4R | |
| SCHEMBL8433615 | 0.87 | LTB4R (0.59) | LTB4R | |
| SCHEMBL8433617 | 0.87 | LTB4R (0.59) | LTB4R | |
| SCHEMBL8916820 | 0.85 | LTB4R (0.57) | LTB4RALDH1A1 | |
| SCHEMBL8430569 | 0.85 | LTB4R (0.47) | LTB4R | |
| SCHEMBL8430585 | 0.84 | LTB4R (0.50) | LTB4R | |
| SCHEMBL8434449 | 0.84 | LTB4R (0.46) | LTB4R | |
| SCHEMBL8433825 | 0.84 | LTB4R (0.48) | LTB4R | |
| SCHEMBL8433096 | 0.84 | LTB4R (0.49) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929096-A | TREATING DISEASES ATTRIBUTING THEIR ORIGIN OR AFFECT TO LEUKOTRIENES, ANTIALLERGENS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |