Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8437751 | 0.91 | ACE2 (0.42) | DNM1ACE2OPRM1 | |
| SCHEMBL8439663 | 0.84 | DNM1 (0.37) | DNM1CYP3A4ACE2L3MBTL1OPRM1 | |
| SCHEMBL8434328 | 0.84 | DNM1 (0.37) | DNM1CYP3A4ACE2L3MBTL1OPRM1 | |
| SCHEMBL9327738 | 0.77 | ACE2 (0.42) | DNM1ACE2OPRM1 | |
| SCHEMBL786298 | 0.77 | CYP3A4 (0.38) | DNM1CYP3A4ACE2L3MBTL1OPRM1 | |
| SCHEMBL27635146 | 0.77 | DNM1 (0.38) | DNM1CYP3A4ACE2L3MBTL1OPRM1 | |
| SCHEMBL8433524 | 0.76 | ACE2 (0.46) | DNM1ACE2OPRM1 | |
| SCHEMBL8436440 | 0.76 | ACE2 (0.46) | DNM1ACE2OPRM1 | |
| SCHEMBL13701664 | 0.75 | — | — | |
| SCHEMBL12112393 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922654-A | TWO OR MORE ORGANOMETALLIC COMPOUNDS WHERE THE METAL IS A TRANSITION METAL OR SEMIMETAL, OR ZINC; FOR EXAMPLE, ZINC DIALKYLDITHIOPHOSPHATE, OR NICKEL DIALKYLDITHIOCARBAMATE; HIGHER LOAD BEARING PROPERTIES, HIGH TEMPERATURE PERFORMANCE | NSK LTD. (JP) | 1999-07-13 | — | — | US | disclosed |
| US-4251425-A | Polycarbonate resin composition | TEIJIN CHEMICALS, LTD. (JP) | 1981-02-17 | — | — | US | disclosed |