Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2994447 | 0.85 | MEN1 (0.40) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL9843774 | 0.80 | MEN1 (0.38) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL3002888 | 0.78 | MEN1 (0.37) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| Water SCHEMBL9016316 | 0.78 | MEN1 (0.37) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL4655189 | 0.77 | MEN1 (0.35) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL13045306 | 0.76 | MEN1 (0.40) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL13046506 | 0.76 | MEN1 (0.36) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL19645490 | 0.76 | MEN1 (0.40) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL22903899 | 0.76 | MEN1 (0.36) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL18556456 | 0.75 | MEN1 (0.38) | MEN1ALDH1A1LMNAALOX12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008074132-A1 | INHIBITORS OF HISTONE DEACETYLASE AND PRODRUGS THEREOF | METHYLGENE INC. (CA) | 2008-06-26 | — | — | WO | disclosed |
| US-20080146623-A1 | INHIBITORS OF HISTONE DEACETYLASE AND PRODRUGS THEREOF | METHYLGENE INC. (CA) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146623-A1 | INHIBITORS OF HISTONE DEACETYLASE AND PRODRUGS THEREOF | HDAC1, HDAC3, HDAC11 | MEN1 1848/4885ALDH1A1 521/4885LMNA 1585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.