Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 9/20 | 0.62 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.61 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.61 |
| ▸ | CTSB | P07858 | 6/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.57 |
| ▸ | TACR1 | P25103 | 2/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436808 | 1.00 | CTSL (0.62) | CTSLITGA4ITGB7CTSBHDAC1 | |
| SCHEMBL8433892 | 1.00 | CTSL (0.62) | CTSLITGA4ITGB7CTSBHDAC1 | |
| SCHEMBL10445399 | 0.93 | CTSL (0.65) | CTSLCTSB | |
| SCHEMBL10445398 | 0.93 | CTSL (0.65) | CTSLCTSB | |
| SCHEMBL11144067 | 0.93 | CTSL (0.65) | CTSLITGA4ITGB7CTSBP2RX7 | |
| SCHEMBL8713258 | 0.93 | CTSL (0.65) | CTSLITGA4ITGB7CTSBP2RX7 | |
| SCHEMBL11138908 | 0.93 | CTSL (0.65) | CTSLITGA4ITGB7CTSBP2RX7 | |
| SCHEMBL951558 | 0.93 | CTSL (0.65) | CTSLITGA4ITGB7CTSBP2RX7 | |
| SCHEMBL11013893 | 0.90 | CTSL (0.58) | CTSLITGA4ITGB7CTSBHDAC1 | |
| SCHEMBL1715348 | 0.90 | CTSL (0.57) | CTSLITGA4ITGB7CTSBP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885816-A | OPTICALLY RESOLVING A RACEMIC MIXTURE OF AMINO ACID DERIVATIVES, COMPRISING USING A NONSPECIFIC CATALYTIC ANTIBODY WHICH ENANTIOSELECTIVELY HYDROLIZES VARIOUS AMINO ACID ESTER DERIVATIVES | PROTEIN ENGINEERING RESEARCH INSTITUTE (JP) | 1999-03-23 | — | — | US | disclosed |
| EP-0765940-A1 | CATALYTIC ANTIBODY WHICH HYDROLYZES AMINO ACID ESTER DERIVATIVE ENANTIOSELECTIVELY | PROTEIN ENGINEERING RESEARCH INSTITUTE (JP) | 1997-04-02 | — | — | EP | disclosed |