Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 7/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434175 | 1.00 | LTB4R (0.43) | LTB4RTERTPTGESALOX5CHRM5 | |
| SCHEMBL8432444 | 0.89 | LTB4R (0.54) | LTB4RTERTALOX5 | |
| SCHEMBL8430558 | 0.87 | LTB4R (0.55) | LTB4RTERTCHRM5CHRM1 | |
| SCHEMBL8432882 | 0.85 | LTB4R (0.57) | LTB4RTERT | |
| SCHEMBL8430426 | 0.84 | LTB4R (0.40) | LTB4RTERT | |
| SCHEMBL8430424 | 0.84 | LTB4R (0.40) | LTB4RTERT | |
| SCHEMBL8434253 | 0.84 | LTB4R (0.58) | LTB4RTERT | |
| SCHEMBL8434470 | 0.83 | LTB4R (0.56) | LTB4RTERT | |
| SCHEMBL8430525 | 0.82 | LTB4R (0.53) | LTB4R | |
| SCHEMBL8434050 | 0.80 | LTB4R (0.51) | LTB4RTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929096-A | TREATING DISEASES ATTRIBUTING THEIR ORIGIN OR AFFECT TO LEUKOTRIENES, ANTIALLERGENS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |