Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 11/20 | 0.56 |
| ▸ | RARB | P10826 | 11/20 | 0.56 |
| ▸ | RARG | P13631 | 10/20 | 0.56 |
| ▸ | IKBKB | O14920 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | GOT1 | P17174 | 1/20 | 0.40 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434304 | 1.00 | RARA (0.56) | RARARARBRARGIKBKBMEN1 | |
| SCHEMBL27499502 | 0.92 | RARA (0.59) | RARARARBRARGIKBKBMEN1 | |
| SCHEMBL8433262 | 0.90 | RARB (0.58) | RARARARBRARGIKBKBMEN1 | |
| SCHEMBL8433266 | 0.90 | RARB (0.58) | RARARARBRARGIKBKBMEN1 | |
| SCHEMBL8432339 | 0.89 | RARA (0.57) | RARARARBRARGIKBKBMEN1 | |
| SCHEMBL8432342 | 0.89 | RARA (0.57) | RARARARBRARGIKBKBMEN1 | |
| SCHEMBL8432317 | 0.88 | RARB (0.60) | RARARARBRARGIKBKBMEN1 | |
| SCHEMBL8432315 | 0.88 | RARB (0.60) | RARARARBRARGIKBKBMEN1 | |
| SCHEMBL8432125 | 0.86 | RARA (0.60) | RARARARBRARGIKBKBMEN1 | |
| SCHEMBL8432129 | 0.86 | RARA (0.60) | RARARARBRARGIKBKBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776881-B1 | Bi-aromatic compounds comprising an adamantyl group in para-position, pharmaceutical and cosmetic compositions containing them and their utilization | CIRD GALDERMA (FR) | 1999-12-08 | — | — | EP | claimed |
| EP-0776881-B1 | Bi-aromatic compounds comprising an adamantyl group in para-position, pharmaceutical and cosmetic compositions containing them and their utilization | CIRD GALDERMA (FR) | 1999-12-08 | — | — | EP | disclosed |
| EP-0776881-A1 | Bi-aromatic compounds comprising an adamantyl group in para-position, pharmaceutical and cosmetic compositions containing them and their utilization | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1997-06-04 | — | — | EP | disclosed |