Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5489927 | 0.85 | HRH3 (0.52) | HRH3ALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL11179141 | 0.85 | HRH3 (0.52) | HRH3ALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL5248213 | 0.84 | HRH3 (0.42) | HRH3ALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL10846103 | 0.82 | HRH3 (0.48) | HRH3ALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL9329891 | 0.77 | SMN1; SMN2 (0.42) | ALDH1A1POLBLMNASMN1; SMN2MEN1 | |
| SCHEMBL11889486 | 0.76 | HRH3 (0.56) | HRH3ALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL15658696 | 0.76 | HRH3 (0.44) | HRH3ALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL11032523 | 0.75 | HRH3 (0.48) | HRH3ALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL27879440 | 0.74 | HRH3 (0.42) | HRH3ALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL3469514 | 0.74 | HRH3 (0.43) | HRH3ALDH1A1MAPTPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101759645-B | P38 inhibitors and methods of use thereof | ARRAY BIOPHARMA INC | 2014-06-25 | — | — | CN | disclosed |
| EP-0587182-B1 | Process for producing compositions for ruminants | KYOWA HAKKO KOGYO KK (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5565212-A | Process for producing compositions for ruminants | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-10-15 | — | — | US | disclosed |
| EP-0587182-A2 | Process for producing compositions for ruminants | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1994-03-16 | — | — | EP | disclosed |