SCHEMBL8434664

SCHEMBL8434664

Cc1c(C)c(O)c(I)c(I)c1O

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11340378 0.86 TTR (0.32) TTR
SCHEMBL19012057 0.83 TTR (0.30) TTR
SCHEMBL5586634 0.83 TTR (0.30) TTR
SCHEMBL19011885 0.83 TTR (0.30) TTR
SCHEMBL21937056 0.81 TTR (0.33) TTR
SCHEMBL19920732 0.81 TTR (0.33) TTR
SCHEMBL5587538 0.76 TTR (0.30) TTR
SCHEMBL19401236 0.74
SCHEMBL8843949 0.74 TTR (0.33) TTR
Durohydroquinone SCHEMBL69786 0.74 ALOX5 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7517471-B2 And benzo[1,2-b:3,4-b']difuran derivatives; liquid crystal media, electrooptical displays; negative Delta epsilon, vertically alligned thin film transistors MERCK PATENT GMBH (DE) 2009-04-14 US disclosed
US-5889185-A Method of synthesizing isoindolequinones and derivatives thereof THE UNIVERSITY OF AKRON (US) 1999-03-30 US disclosed
WO-1998046567-A1 METHOD OF SYNTHESIZING ISOINDOLEQUINONES AND DERIVATIVES THEREOF THE UNIVERSITY OF AKRON (US) 1998-10-22 WO disclosed