Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.52 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695482 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL6692594 | 0.91 | ALDH1A1 (0.52) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL6693401 | 0.91 | PDE4D (0.49) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL8430735 | 0.91 | ALDH1A1 (0.52) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL6691941 | 0.90 | ALDH1A1 (0.62) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL6695732 | 0.87 | PDE4D (0.49) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL6695733 | 0.86 | PDE4D (0.36) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL7595295 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL6693745 | 0.82 | PDE4D (0.48) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL6693793 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KDM4EHKDC1TDP1SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5906989-A | TREATING GLAUCOMA | ALLERGAN SALES, INC. (US) | 1999-05-25 | — | — | US | disclosed |