SCHEMBL8434992

SCHEMBL8434992

CCCCC(CCC)CO[PH](=O)OCC(CCC)CCCC

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CA2 P00918 5/20 0.39
CA1 P00915 2/20 0.39
CA12 O43570 1/20 0.39
CA7 P43166 1/20 0.39
CA14 Q9ULX7 1/20 0.39
TSHR P16473 4/20 0.38
TDP1 Q9NUW8 2/20 0.38
ATM Q13315 1/20 0.38
ALDH1A1 P00352 5/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
RECQL P46063 1/20 0.32
LMNA P02545 2/20 0.31
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP14 P50281 1/20 0.30
FDPS P14324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9637513 0.96 CYP3A4 (0.44) CYP3A4L3MBTL1CA2CA1CA12
SCHEMBL26983493 0.94 LMNA (0.39) CYP3A4L3MBTL1CA2CA1CA12
SCHEMBL28532180 0.90 LMNA (0.43) CYP3A4L3MBTL1CA2TSHRTDP1
SCHEMBL329554 0.88 CYP3A4 (0.55) CYP3A4L3MBTL1CA2TSHRTDP1
SCHEMBL28689341 0.86 CYP3A4 (0.53) CYP3A4L3MBTL1CA2TSHRTDP1
SCHEMBL30250357 0.86 CYP3A4 (0.53) CYP3A4L3MBTL1CA2TSHRTDP1
Hexane SCHEMBL28501779 0.86 CYP3A4 (0.53) CYP3A4L3MBTL1CA2TSHRTDP1
SCHEMBL30249980 0.86 CYP3A4 (0.53) CYP3A4L3MBTL1CA2TSHRTDP1
SCHEMBL31416102 0.86 CYP3A4 (0.53) CYP3A4L3MBTL1CA2TSHRTDP1
SCHEMBL28822364 0.86 CYP3A4 (0.53) CYP3A4L3MBTL1CA2TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5922654-A TWO OR MORE ORGANOMETALLIC COMPOUNDS WHERE THE METAL IS A TRANSITION METAL OR SEMIMETAL, OR ZINC; FOR EXAMPLE, ZINC DIALKYLDITHIOPHOSPHATE, OR NICKEL DIALKYLDITHIOCARBAMATE; HIGHER LOAD BEARING PROPERTIES, HIGH TEMPERATURE PERFORMANCE NSK LTD. (JP) 1999-07-13 US disclosed