Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 13/20 | 0.52 |
| ▸ | CNR1 | P21554 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843772 | 0.96 | CNR2 (0.53) | TSHRTDP1L3MBTL1CNR2CNR1 | |
| SCHEMBL842785 | 0.95 | TSHR (0.54) | TSHRTDP1L3MBTL1CNR2CNR1 | |
| SCHEMBL843905 | 0.88 | ALDH1A1 (0.53) | TSHRTDP1CNR2CNR1ALDH1A1 | |
| SCHEMBL3410243 | 0.83 | CNR2 (0.60) | TSHRCNR2CNR1ALDH1A1 | |
| SCHEMBL3408272 | 0.82 | CNR2 (0.64) | CNR2CNR1 | |
| SCHEMBL3407492 | 0.81 | CNR2 (0.63) | CNR2CNR1 | |
| SCHEMBL843172 | 0.81 | CNR2 (0.57) | TSHRCNR2CNR1ALDH1A1HSD17B10 | |
| SCHEMBL858856 | 0.76 | CNR2 (0.64) | CNR2CNR1 | |
| SCHEMBL843912 | 0.75 | CNR2 (0.67) | CNR2CNR1 | |
| SCHEMBL859522 | 0.74 | CNR2 (0.66) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432763-A1 | 1,4 DIHYDROPYRIDINE DERIVATIVES AND THEIR USES | Université de Lille 2 Droit et Santé (FR) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133973-A1 | 1,4 DIHYDROPYRIDINE DERIVATIVES AND THEIR USES | UNIVERSITE LILLE 2 DROIT ET SANTE (FR) | 2010-11-25 | — | — | WO | disclosed |