Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 15/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27674647 | 0.84 | TACR1 (0.57) | TACR1APOBEC3ARECQLAPOBEC3G | |
| SCHEMBL6575758 | 0.76 | TACR1 (0.72) | TACR1APOBEC3ARECQLAPOBEC3GGRIN1 | |
| SCHEMBL6042718 | 0.76 | TACR1 (0.55) | TACR1APOBEC3ARECQLAPOBEC3G | |
| SCHEMBL23892111 | 0.76 | TACR1 (0.64) | TACR1APOBEC3ARECQLAPOBEC3GGRIN1 | |
| SCHEMBL7227119 | 0.74 | TACR1 (0.76) | TACR1APOBEC3ARECQLAPOBEC3GGRIN1 | |
| SCHEMBL8435472 | 0.72 | TACR1 (0.53) | TACR1APOBEC3ARECQLAPOBEC3GGRIN1 | |
| SCHEMBL10737198 | 0.71 | TACR1 (0.64) | TACR1APOBEC3ARECQLAPOBEC3GGRIN1 | |
| SCHEMBL8804899 | 0.70 | TACR1 (0.47) | TACR1APOBEC3ARECQLAPOBEC3GGRIN1 | |
| SCHEMBL6411370 | 0.70 | TACR1 (1.00) | TACR1 | |
| SCHEMBL10736720 | 0.68 | TACR1 (0.59) | TACR1APOBEC3ARECQLAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998433-A | THERAPY FOR HYPERLIPIDEMIA; ATHEROSCLEROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| CN-1160403-A | Substd. heterobicyclic alkyl amines and their use as squalene oxide cyclase inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-09-24 | — | — | CN | disclosed |