Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 14/20 | 0.72 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7227119 | 0.88 | TACR1 (0.76) | TACR1SIGMAR1GRIN1GRIN2BAPOBEC3A | |
| SCHEMBL23892111 | 0.85 | TACR1 (0.64) | TACR1SIGMAR1GRIN1GRIN2BAPOBEC3A | |
| SCHEMBL6411370 | 0.84 | TACR1 (1.00) | TACR1 | |
| SCHEMBL10737198 | 0.83 | TACR1 (0.64) | TACR1SIGMAR1GRIN1GRIN2BAPOBEC3A | |
| SCHEMBL6413713 | 0.80 | TACR1 (1.00) | TACR1 | |
| SCHEMBL10736720 | 0.79 | TACR1 (0.59) | TACR1APOBEC3ARECQLAPOBEC3GKDM4E | |
| SCHEMBL6943959 | 0.79 | TACR1 (0.62) | TACR1SIGMAR1GRIN1GRIN2B | |
| SCHEMBL467266 | 0.79 | TACR1 (0.62) | TACR1SIGMAR1GRIN1GRIN2B | |
| SCHEMBL16836134 | 0.79 | SIGMAR1 (0.64) | TACR1SIGMAR1GRIN1GRIN2B | |
| SCHEMBL385325 | 0.79 | TACR1 (0.62) | TACR1SIGMAR1GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934928-B1 | CYCLIC AMINE DERIVATIVES | SANKYO CO (JP) | 2004-10-13 | — | — | EP | disclosed |
| US-6610708-B1 | Anticoagulants | SANKYO COMPANY, LIMITED (JP) | 2003-08-26 | — | — | US | disclosed |
| EP-1063230-B1 | CYCLIC AMINO COMPOUNDS | SANKYO CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-1063230-A1 | CYCLIC AMINO COMPOUNDS | Sankyo Company Limited (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-6087379-A | AN ANTICOAGULANT FOR THE TREATMENT AND PREVENTION OF DISEASES AS EMBOLISM, THROMBOSIS OR ARTERIOSCLEROSIS | SANKYO COMPANY, LIMITED (JP) | 2000-07-11 | — | — | US | disclosed |
| EP-0934928-A1 | CYCLIC AMINE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1999-08-11 | — | — | EP | disclosed |