SCHEMBL8435513

SCHEMBL8435513

CC(CC(C#N)N(CC#N)CC#N)C(C#N)N(CC#N)CC#N

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6545398 0.79 CYP1A2 (0.43) CYP1A2MAPK1
SCHEMBL8024855 0.78 CYP1A2 (0.37) CYP1A2MAPK1
SCHEMBL6544383 0.70 CYP1A2 (0.36) CYP1A2MAPK1
SCHEMBL9762839 0.66 CYP1A2 (0.31) CYP1A2MAPK1
SCHEMBL16580145 0.65 CYP1A2 (0.44) CYP1A2MAPK1
SCHEMBL1582129 0.65 CYP1A2 (0.44) CYP1A2MAPK1
SCHEMBL12703835 0.64 CYP1A2 (0.48) CYP1A2MAPK1
SCHEMBL8773721 0.61 TSHR (0.38)
SCHEMBL21162352 0.60 CYP1A2 (0.39) CYP1A2MAPK1
SCHEMBL23735583 0.57 MAPK1 (0.41) CYP1A2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6008176-A AS TEXTILE DETERGENT BUILDERS IN POWDER DETERGENT FORMULATIONS AND AS CALCIUM SEQUESTRANTS IN ORAL HYGIENE PRODUCTS BASF AKTIENGESELLSCHAFT (DE) 1999-12-28 US disclosed
US-6005141-A ALSO USED AS TEXTILE DETERGENT BUILDERS IN POWDER DETERGENT FORMULATIONS AND AS CALCIUM SEQUESTRANTS IN ORAL HYGIENE PRODUCTS; REACTING 2-SUBSTITUTED GLYCINES OR 2-SUBSTITUTED GLYCINONITRILES WITH FORMALDEHYDE AND HYDROGEN CYANIDE BASF AKTIENGESELLSCHAFT (DE) 1999-12-21 US disclosed
US-5786313-A ALPHA-ALANINE-N,N-DIACETIC ACID; INDUSTRIAL CLEANING; DISHWASHING BASF AKTIENGESELLSCHAFT (DE) 1998-07-28 US disclosed