SCHEMBL23735583

SCHEMBL23735583

CC(C)N(CC#N)CCC#N

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.41
CYP1A2 P05177 2/20 0.41
TSHR P16473 2/20 0.37
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LCK P06239 1/20 0.32
NLRP3 Q96P20 1/20 0.32
DPP4 P27487 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7319284 0.90 TSHR (0.40) MAPK1CYP1A2TSHRALDH1A1TDP1
SCHEMBL12703835 0.84 CYP1A2 (0.48) MAPK1CYP1A2TSHRALDH1A1DPP4
SCHEMBL11668657 0.83 TSHR (0.40) MAPK1CYP1A2TSHRALDH1A1TDP1
SCHEMBL13601936 0.81 TSHR (0.44) TSHRALDH1A1TDP1LCKNLRP3
SCHEMBL13601934 0.78 TSHR (0.52) TSHRLCK
SCHEMBL2562308 0.76 TSHR (0.31) TSHRALDH1A1NLRP3
SCHEMBL5145272 0.75 TSHR (0.37) MAPK1CYP1A2TSHRALDH1A1TDP1
SCHEMBL24577584 0.75 PIK3CD (0.39) MAPK1CYP1A2
SCHEMBL16750038 0.74 ALDH1A1 (0.36) TSHRALDH1A1TDP1NLRP3
SCHEMBL29957650 0.74 ALDH1A1 (0.31) TSHRALDH1A1NLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3645507-B1 PROCESS FOR MANUFACTURING A COMPLEXING AGENT BASF SE (DE) 2021-08-11 EP disclosed