Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | RGS4 | P49798 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930835 | 0.95 | NR1H2 (0.44) | NR1H2NR1H3PTGS1PTGS2PTPN1 | |
| SCHEMBL7936995 | 0.94 | NR1H2 (0.47) | NR1H2NR1H3PTGS1PTGS2PTPN1 | |
| SCHEMBL7930947 | 0.94 | NR1H2 (0.47) | NR1H2NR1H3PTGS1PTGS2PTPN1 | |
| SCHEMBL7933454 | 0.94 | NR1H2 (0.47) | NR1H2NR1H3PTGS1PTGS2PTPN1 | |
| SCHEMBL7932654 | 0.94 | NR1H2 (0.47) | NR1H2NR1H3PTGS1PTGS2PTPN1 | |
| SCHEMBL7932652 | 0.94 | NR1H2 (0.47) | NR1H2NR1H3PTGS1PTGS2PTPN1 | |
| SCHEMBL7933400 | 0.94 | NR1H2 (0.47) | NR1H2NR1H3PTGS1PTGS2PTPN1 | |
| SCHEMBL7933380 | 0.94 | NR1H2 (0.47) | NR1H2NR1H3PTGS1PTGS2PTPN1 | |
| SCHEMBL7934341 | 0.94 | NR1H2 (0.47) | NR1H2NR1H3PTGS1PTGS2PTPN1 | |
| SCHEMBL7937030 | 0.94 | NR1H2 (0.47) | NR1H2NR1H3PTGS1PTGS2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981662-A | VULCANIZATES FOR USE IN SIDEWALL, TREAD, CARCASS PLY, WIRECOAT OR OVERLAY COMPOUNDS FOR TIRES; IMPART ANTI-REVERSION AND ANTIFATIGUE PROPERTIES IN THE RUBBER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0908489-A2 | Rubber compounds containing polymeric bis-succinimide polysulfides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-04-14 | — | — | EP | disclosed |