Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 3/20 | 0.41 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18580338 | 0.87 | PSEN1 (0.42) | BCHEPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL18580339 | 0.87 | PSEN1 (0.42) | BCHEPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL18580336 | 0.87 | PSEN1 (0.42) | BCHEPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL18580630 | 0.87 | PSEN1 (0.42) | BCHEPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL18580628 | 0.87 | PSEN1 (0.42) | BCHEPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8432901 | 0.84 | PDE4D (0.44) | MERTKAXLBCHEPDE4DSLC6A2 | |
| SCHEMBL9074022 | 0.81 | PDE4D (0.46) | MERTKAXLBCHEPDE4DSLC6A2 | |
| SCHEMBL9074021 | 0.81 | PDE4D (0.46) | MERTKAXLBCHEPDE4DSLC6A2 | |
| SCHEMBL6671511 | 0.81 | PDE4D (0.46) | MERTKAXLBCHEPDE4DSLC6A2 | |
| SCHEMBL6669362 | 0.81 | PDE4D (0.46) | MERTKAXLBCHEPDE4DSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36385-E | TREATMENT OF TUMORS, ENHANCING IMMUNITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0288888-B1 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-4925929-A | ANTITUMOR AGENTS | ONO PHARMACEUTICAL CO. LTD. (JP) | 1990-05-15 | — | — | US | disclosed |