Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436087 | 1.00 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2FKBP1ATSHRNPC1 | |
| SCHEMBL22836694 | 0.73 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL15751215 | 0.73 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2FKBP1ATSHRNPC1 | |
| SCHEMBL304194 | 0.73 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2FKBP1ATSHRNPC1 | |
| SCHEMBL304428 | 0.73 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2FKBP1ATSHRNPC1 | |
| SCHEMBL15751216 | 0.73 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2FKBP1ATSHRNPC1 | |
| SCHEMBL304195 | 0.73 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2FKBP1ATSHRNPC1 | |
| SCHEMBL5007203 | 0.72 | ALDH1A1 (0.62) | ALDH1A1TSHRGAA | |
| SCHEMBL2992037 | 0.72 | ALDH1A1 (0.62) | ALDH1A1TSHRGAA | |
| SCHEMBL15751482 | 0.72 | CYP3A4 (0.41) | ALDH1A1SMN1; SMN2TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948793-A | 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling neurotransmitter release | ABBOTT LABORATORIES (US) | 1999-09-07 | — | — | US | disclosed |
| US-5914328-A | CONTROL DOPAMINE RELEASE, ACTIVATE CHOLINERGIC CHANNELS | ABBOTT LABORATORIES (US) | 1999-06-22 | — | — | US | disclosed |