Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 9/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | KRAS | P01116 | 2/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.38 |
| ▸ | POLG | P54098 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.36 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436518 | 0.91 | P2RX3 (0.40) | P2RX3IMPDH2KRASP2RX2P2RX1 | |
| SCHEMBL8440907 | 0.89 | P2RX3 (0.42) | P2RX3IMPDH2P2RX2P2RX1P2RX4 | |
| SCHEMBL8435325 | 0.88 | P2RX3 (0.42) | P2RX3IMPDH2P2RX2P2RX1P2RX4 | |
| SCHEMBL8439125 | 0.87 | P2RX3 (0.39) | P2RX3IMPDH2P2RX2P2RX1P2RX4 | |
| SCHEMBL8439668 | 0.86 | P2RX3 (0.36) | P2RX3KRASP2RX2P2RX1P2RX4 | |
| SCHEMBL8440833 | 0.86 | P2RX3 (0.44) | P2RX3P2RX2P2RX1P2RX4TGM2 | |
| SCHEMBL8439436 | 0.86 | FNTA (0.37) | P2RX3P2RX2P2RX1P2RX4 | |
| SCHEMBL8441069 | 0.86 | POLG (0.51) | P2RX3IMPDH2KRASP2RX2P2RX1 | |
| SCHEMBL8436303 | 0.84 | P2RY2 (0.43) | P2RX3IMPDH2P2RX2P2RX1P2RX4 | |
| SCHEMBL8440013 | 0.82 | P2RX3 (0.41) | P2RX3IMPDH2P2RX2P2RX1P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5902793-A | ADMINISTERING TO MAMMAL GAMMA-MONOALKYL- OR GAMMA-ALKENYL-NUCLEOSIDE OR DEOXYNUCLEOSIDE TRIPHOSPHATE | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 1999-05-11 | — | — | US | claimed |
| US-5902793-A | ADMINISTERING TO MAMMAL GAMMA-MONOALKYL- OR GAMMA-ALKENYL-NUCLEOSIDE OR DEOXYNUCLEOSIDE TRIPHOSPHATE | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 1999-05-11 | — | — | US | disclosed |
| US-5639653-A | ADMINISTERING MONOALKYL- OR ALKENYL-PYROPHOSPHATE TO MAMMAL TO STIMULATE LYMPHOCYTE CELL GROWTH AND ENHANCE IMMUNE RESPONSE | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, A DIVISION OF YESHIVA UNIVERSTIY (US) | 1997-06-17 | — | — | US | disclosed |