Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.35 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574217 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| SCHEMBL9574299 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| SCHEMBL8607827 | 0.94 | ALDH1A1 (0.40) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| SCHEMBL8577735 | 0.94 | ALDH1A1 (0.40) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| SCHEMBL8438310 | 0.89 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| SCHEMBL8438306 | 0.89 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL8438116 | 0.89 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL8438164 | 0.89 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL8438115 | 0.89 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| SCHEMBL7459542 | 0.88 | GRIN2B (0.38) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |