Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 5/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.42 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8440542 | 0.99 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3KDM1AKCNH2 | |
| SCHEMBL15086907 | 0.83 | UHRF1 (0.45) | KDM1A | |
| SCHEMBL16453454 | 0.80 | KDM4E (0.44) | KDM1AIRAK4 | |
| SCHEMBL16453504 | 0.79 | KDM4E (0.46) | — | |
| SCHEMBL17136283 | 0.78 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KDM1AKCNH2 | |
| SCHEMBL4828300 | 0.77 | CHRNB2 (0.46) | KCNH2ROCK2ROCK1CHRNB2CHRNA4 | |
| SCHEMBL8277614 | 0.77 | GRM4 (0.42) | IRAK4 | |
| SCHEMBL427054 | 0.75 | HRH3 (0.44) | SLC6A4 | |
| SCHEMBL24176193 | 0.75 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3KDM1AKCNH2 | |
| SCHEMBL17277362 | 0.75 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3KDM1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914328-A | CONTROL DOPAMINE RELEASE, ACTIVATE CHOLINERGIC CHANNELS | ABBOTT LABORATORIES (US) | 1999-06-22 | — | — | US | disclosed |